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Patient Information Leaflet on
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Tagamet
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 (cimetidine) Injection
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This leaflet tells you about 'Tagamet' Injection. Please read it before you are given your treatment.
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If there is anything you do not understand, or if you want to know more about your treatment, ask your doctor or nurse.
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Please keep this leaflet. You may want to read it again.
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What is in ‘Tagamet’ Injection?
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Your injection contains the active ingredient cimetidine. Each ampoule contains 200 milligrammes (mg) cimetidine in 2 ml solution. Your injection also contains inactive ingredients. These are concentrated hydrochloric acid (E507) and water for injections.
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Your medicine is available in boxes of 20 ampoules.
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What is ‘Tagamet’ and how does it work?
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Your medicine is known as a histamine H2 antagonist. It works by reducing the natural production of acid in the stomach.
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Who makes ‘Tagamet’ Injection?
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The Product Licence/Authorisation Holder is Smith Kline &amp; French Laboratories Ltd, trading as SmithKline Beecham Pharmaceuticals, Welwyn Garden City, Hertfordshire, England AL7 1EY.
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Your medicine is manufactured by SmithKline Beecham Pharma GmbH, Gronau, Germany.
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What is ‘Tagamet’ used for?
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Your medicine is used to treat and relieve the symptoms of stomach and duodenal ulcers, oesophageal reflux disease and the Zollinger-Ellison syndrome.
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It will also help in the healing of ulcers and reduce the inflammation due to these conditions.
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Your medicine may also be prescribed for a range of other medical conditions where the reduction of acid production in the stomach is needed.
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Before you are given your medicine
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If you answer 
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Yes
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 to any of the following questions, tell your doctor or nurse 
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BEFORE
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 you are given your medicine. You may need to be given another medicine or the dose may need to be changed.
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Are you allergic to 'Tagamet' (cimetidine)?
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Do you have a kidney problem?
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Do you have a blood disease?
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Have you had a stomach ulcer or a duodenal ulcer before? You should discuss this with your doctor, particularly if you are taking a non-steroidal anti-inflammatory drug (NSAID).
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Are you pregnant, or do you think you may be?
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Are you breast feeding?
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Are you taking any of the medicines listed below?
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Medicines to thin your blood (anticoagulants)
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Medicines to prevent fits (anticonvulsants), e.g. phenytoin
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Theophylline
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Lignocaine
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How will you be given your medicine?
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Your medicine will be given to you by injection into a muscle, or slowly into a vein. The length of treatment will be decided by your doctor.
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The usual adult dose of 'Tagamet' by injection is 200-400 mg every four to six hours.
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The dose of 'Tagamet' for children varies with body weight. The usual dose is 25-30 mg for each kg of body weight each day. This is given in divided doses. The maximum recommended dose of 'Tagamet' is 2.4 g a day.
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If you think you have missed an injection or that you have been given too much, speak to a nurse or a doctor.
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What unwanted side effects might your medicine cause?
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Side effects with your medicine are usually mild and do not last long. The most common unwanted effects are diarrhoea, dizziness, rash or tiredness.
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Other, more rare side effects. are confusion, breast enlargement in <CB n=2> men, blood changes, kidney disorders, liver disorders, inflammation of the pancreas, fever, headache, aching muscles, aching joints, heart effects and impotence. All these side effects should disappear when treatment is stopped.
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Very rarely, allergic reactions (rash, itching, shortness of breath and low blood pressure) and hair loss have occurred.
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Tell your doctor if you notice any of these effects or any other unwanted effects not mentioned above
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Storing your medicine
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Your medicine should be stored below 30°C and protected from light, until it is administered to you.
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The doctor or nurse should check that the expiry date on the pack has not been passed.
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Leaflet prepared May 1995 'Tagamet' and the SB logo are trade marks &copy; 1995 SmithKline Beecham Pharmaceuticals25 5518 0
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