<!DOCTYPE DOCUMENT SYSTEM "icon.dtd" []>

<DOCUMENT author="perl program" datec=020199 title="leaflet" book="ABPI" edition="1996-97" section="company">
<DIV type=0>

<HEAD justified="center" >
'TENORET' 50
</HEAD>


<BLOCK justified=center>

<EMPH weight="bold">
Please read this leaflet carefully before you take your
</EMPH>
 
<EMPH weight="bold">
medicine. This leaflet only gives a summary of the 
<EMPH weight="bold">
information available on your medicine.
</EMPH>

</EMPH>

</BLOCK>


<BLOCK justified=center>

<EMPH weight="bold">
If you have any questions or are not sure about 
<EMPH weight="bold">
anything, ask your doctor or pharmacist.
</EMPH>

</EMPH>

</BLOCK>


<BLOCK justified=center>
The name of your medicine is 'Tenoret' 50.
</BLOCK>


<BLOCK justified=center>
The active ingredients are atenolol and chlorthalidone.
</BLOCK>


<BLOCK justified=center>
'Tenoret' 50 is produced as tablets which contain 50 mg of atenolol and 12.5 mg of chlorthalidone.
</BLOCK>


<BLOCK justified=center>
Your medicine also contains the following inactive ingredients:
</BLOCK>


<BLOCK justified=center>
gelatin, iron oxide, macrogol, magnesium carbonate, magnesium stearate, methylhydroxypropylcellulose, sodium lauryl sulphate and maize starch.
</BLOCK>

<DIV type=1>

<HEAD justified="center" >
'Tenoret' 50 tablets are produced in packs of 28, 30, 500 and
</HEAD>


<BLOCK justified=center>
504 tablets. Some of the pack sizes quoted are not available.
</BLOCK>


<BLOCK justified=center>
Atenolol is one of a group of drugs called beta blockers. It has effects on the heart and circulation. Chlorthalidone is one of a group of drugs called diuretics. It increases the amount of urine produced by the kidneys.
</BLOCK>


<BLOCK justified=center>
The product licence holder and manufacturer of 'Tenoret' 50 is:
</BLOCK>


<BLOCK justified=center>

<EMPH weight="bold">
ZENECA Limited
</EMPH>
 Macclesfield Cheshire United Kingdom 'Tenoret' 50 is used to treat hypertension (high blood pressure).
</BLOCK>


<BLOCK>
Do not take Tenoret 50 i' YoU have previoushy had an allergic reeceon to n or to atenolol or chlonhalidone Tenoret 50 should not be taken by people whh heanfailure which is not under contol or with cenain of her condeions such as hean block, very slow or very irregular hean beats, very low blood pressure or very poor circulaton. h should also not be taken bY people whn have phaeochromocytoma which is not being reatedorbYpeoplewhohavemetabolicacidosis.Yourdoctorwillknowaboutthesecondib'ons Do not take Aenoret 50 it vou aro pregnant or d vou are breast feeding a baby
</BLOCK>


<BLOCK>
DovouhaveapancularrypeolchestpaincalledPnnzmetal'sangina?ltsoStellyourdoctor Do vou have asthma or do vou get allergic reactons to such things as insect sangs7 If so, tell y vur doctor Do vou have d abetes? Tenolef 50 maV change your normal response to low blood sugar, which usually involves an increase ill hean rate Dp you have thyrutoxi osis7 Tenoret SO may hide fSe symptoms of fhyrotot icosis.
</BLOCK>


<BLOCK>
DovouhavekidlleYproblems71tsoStalktovourdoctorbecausevoumayneedtohavesomecheckupsduringeourtteatment Are vou taking anV uther medicines7 1t so, tell your doctor. Tenoref 50 can intef ere wrth fhe achon of some odher drugs and some drugs can have an eHect on Tenoref 50 The drugs which can cause some problems when taken together wnh Tenoref 50 are verapamil, diXdarem, ndedipine (which are used to treat hypenension or angina), disopyramide llor irregular hean beatsi, digo on if or hean failurel, adrenaline {a hean sdmulant), ibupr :fen and indomethacin ltor pain and Ililammation) and lith vIm RPr depressionl AIP yntl takinq a drilg callcd clonid~ne If or hypenension or migraine)7 11 you ale taking clonidine and Tenolet 50 together, vou must not stop taking clorlidine unless vollr doctos tlells yo l lo dg s 1e it becomes necessary tor vou to stop taking the elonidine, your doctor wiil give VoU careful instructions on how to do it It you go into hospital tu have an operaton, tell ff e anaestheost ol fhe medicaj staff fhat VoU ale taking Tenoret so Vou med ine is un ikeiy to a dect your abi dY to dn te or to operate machinery. Howeyer, some people may occasionally feel di tzy or uled when taking Tenoret Tenoref 50 tablets should be swallowed FoDow yeur doctor s inst uctons about when and how tst Uke your medicine Also read fhe label Your phammacist can also help if you are not sure Your doctor will have decided what dose vou should hake each day depending on ysur cond don. The usual daihy dose for an 2duh is one tablet |t vou forget to take voul medicine. take voul dose when you remember and fhen take your netet dose at dhe usual ome Don t take two doses at fhe same tme If you are worried. ask your doctol ol phammacist tor ad ice
</BLOCK>


<BLOCK>
If you accidentally take an overdose of your medicine, eAher ca9 your doctpr straight away, or go to your nearest hospital casuaRy depanment Aiways take any remaininitablets,dhe containerandShelabelwhhyoursothatthe medicine can bendentthed.
</BLOCK>


<BLOCK>
nn not sioo takino vour medicine wnhout taSbno tp vour docpor hrst In some cases. n may be necessary to stop tabng the medicine gradualhy As wsth alj medicines, undosirabie events can sometmes be etepenenced wnh Tenoref S0. Occasionalhy, a few people can suYer hrom cold hands and feeg tredness, slow hean beat headache. dry mourh, nausea, diarrhoea, disturbed sleep, fhinning of dhe hair, mood changes, conhusion. psychoses or hallucinanons. bruising mole easily or purplish marks on fhe skin, nngl~ng of fhe hands, dry eyes, disturbances of vision, skin rashes, worsening of psoriasis or dittiness panicularly whell standing up Dther possible events which may occur in suscepuble people are numboess and spasm in fhe hngers IRaymaud s phenomenon), hean block lwhich can cause dittiness or fainong), wersening of hean failure in people with hean failure, worsening of breathing dihEcuRdes in people whh asUbma or breathing problems or worsening of fbe circuladon in people wnh poor circulaecn Dther possible events are a reducton in fhe amoUDt of potassium in the blood, an increase in the amount of unc acid in the bl:od or a reduction in dhe number of whne blood cells Yourdoctor mEytake blood samples every so ohen to check on these levels
</BLOCK>


<BLOCK>
Do not be alarm d by th s ist of possibie events You ntay not have any f ffem.
</BLOCK>


<BLOCK>
Checkthe ettpirydate on the canon and don tusethe medicine aherthatdate.
</BLOCK>


<BLOCK>
Keep V° medicine in a sale place where children cannot see it or reach t Your medicine could harm fhem Keep your modicine below 25°C and awaV from strong light and dampness
</BLOCK>


<BLOCK>
H Vour doctor de cides to stop treatment return any leh-over tablets to your phanmacist Only keep fhem if fhe doctor tells Y°U to Date ot niepalation ol leadet: June 1595 This leallet does not contain fhe complete infommadon on Tenoref SO If yeu have any quesdons, or are not sure about anything, ask your doctor or pharmacist
</BLOCK>


<BLOCK>
Remember: This medicine is for you Dnly a doctor can prescribe hfor you Never give n so someone else It mayharm dhem even if their symptoms 
<EMPH weight="bold">
are the 
</EMPH>
same as VoIIrS The Inlorneation applies onN to Teliplet 50
</BLOCK>


<BLOCK>
'Tenoret' 50 is a trademark.
</BLOCK>


<BLOCK>
5/lE/UK/1014708
</BLOCK>

</DIV>

</DIV>

</DOCUMENT>
