<!DOCTYPE DOCUMENT SYSTEM "icon.dtd" []>

<DOCUMENT author="perl program" datec=020199 title="leaflet" book="ABPI" edition="1996-97" section="company">
<DIV type=0>

<HEAD weight="bold" >
What you should know about Syntopressin
</HEAD>


<BLOCK>
Please read this leaflet carefully before you stay using this medicine even it you have already used 
<EMPH weight="bold">
Syntopressin 
</EMPH>
Nasal Spray before. This leaflet provides a summary of the information available on your medicine. If you have any questions or are unsure about anything, ask your doctor or pharmacist (chemist).
</BLOCK>


<BLOCK>
The name of your medicine is 
<EMPH weight="bold">
Syntopressin
</EMPH>
.
<EMPH weight="bold">
 
</EMPH>
It contains lypressin, and it is used to treat diabetes insipidus. This condition is characterised by the production at large amounts of urine.
</BLOCK>

<DIV type=1>

<HEAD weight="bold" >
Things to remember about Syntopressin    
</HEAD>


<PB n=1>


<CB n=1>


<FIGURE></FIGURE>


<CB n=2>


<LIST type="bulleted">

<ITEM>

<BLOCK>
.
</BLOCK>

</ITEM>

</LIST>

<PB n=2>
<CB n=1>
<FIGURE></FIGURE>
<CB n=2>


<BLOCK>

<EMPH weight="bold">
Do not stop taking your medicine unless your doctor tells you to.
</EMPH>

</BLOCK>

<PB n=3>
<CB n=1>
<FIGURE></FIGURE>
<CB n=2>

<BLOCK>

<EMPH weight="bold">
If you start to take other medicines make sure your doctor knows.
</EMPH>

</BLOCK>

<PB n=4>
<CB n=1>
<FIGURE></FIGURE>
<CB n=2>
<DIV type=2>

<HEAD ltag="bullet" >
*    
</HEAD>




<BLOCK>

<EMPH weight="bold">
Keep your medicine away from children.
</EMPH>

</BLOCK>

<PB n=6>
<CB n=1>

<BLOCK>
You will find more about your medicine inside this leaflet. 
</BLOCK>


<BLOCK>
Your medicine is called 
<EMPH weight="bold">
Syntopressin
</EMPH>
. It is used to treat diabetes insipidus, a condition which is characterised by the passing of large amounts of urine.
</BLOCK>


</DIV>
<DIV type=2>

<HEAD ltag="bullet" >
Before taking your medicine
</HEAD>




<BLOCK>
If the answer is yes to any of the following questions, please tell your doctor or pharmacist before starting your medicine.
</BLOCK>


<LIST type="ordered">

<ITEM>

<BLOCK>
Have you ever used this medicine before and been upset by it?
</BLOCK>

</ITEM>


<ITEM>

<BLOCK>
Do you suffer from heart disease, high blood pressure, hardening of the arteries or circulation problems?
</BLOCK>

</ITEM>


<ITEM>

<BLOCK>
Do you suffer from kidney disease?
</BLOCK>

</ITEM>


<ITEM>

<BLOCK>
Do you suffer from epilepsy (fits) or bronchial asthma?
</BLOCK>

</ITEM>


<ITEM>

<BLOCK>
Are you taking any other medicines (particularly carbamazepine, chlorpropamide, clofibrate or lithium)?
</BLOCK>

</ITEM>


<ITEM>

<BLOCK>
Are you due to have an operation where you would need a general anaesthetic?
</BLOCK>

</ITEM>

</LIST>



<BLOCK>
Tell your doctor if you are pregnant or become pregnant during your treatment.
</BLOCK>


<BLOCK>
Do not breast feed while using this medicine.
</BLOCK>


</DIV>

</DIV>
<DIV type=1>

<HEAD weight="bold" >
Using your medicine
</HEAD>


<BLOCK>
This medicine is only available from your doctor.
</BLOCK>


<BLOCK>
Use only the amount directed by your doctor. The label wit tell you how much to use and how often.
</BLOCK>


<BLOCK>
If it does not or you are not sure ask your doctor or pharmacist.
</BLOCK>


<BLOCK>
Before you use the spray for the first time allow it to reach room temperature.
</BLOCK>


</DIV>
<DIV type=1>

<HEAD weight="bold" >
Instructions for use 
</HEAD>


<FIGURE></FIGURE>


<LIST type="ordered">

<ITEM>

<BLOCK>
Remove the cap
</BLOCK>

</ITEM>


<ITEM>

<BLOCK>

<EMPH weight="bold">
For the first time 
</EMPH>
only prime the device by squeezing the actuator several times until a cloud of spray appears.
</BLOCK>

</ITEM>


<ITEM>

<BLOCK>
Sit down and hold the bottle upright, insert into the nostril and give one firm squeeze, whilst inhaling gently through the nose. This should be repeated as recommended by your doctor. You should alternate nostrils for each application of the spray
</BLOCK>

</ITEM>


<ITEM>

<BLOCK>
Replace the cap after use.
</BLOCK>

</ITEM>

</LIST>



<BLOCK>
If you target a dose, spray another as soon as you remember, unless it is almost time for your next dose, then go on as before.
</BLOCK>


<BLOCK>

<EMPH weight="bold">
Overdose: 
</EMPH>
If you accidentally use too much of your medicine, tell your doctor immediately or go to the nearest Casually Department.
</BLOCK>

<DIV type=2>

<HEAD ltag="bullet" >
*After taking your medicine
</HEAD>




<BLOCK>
Most people benefit from this medicine but a few people can be upset by it. If you get any of the following, tell your doctor:
</BLOCK>

<DIV type=3>

<HEAD>
Nausea
</HEAD>


<BLOCK>
If you develop any other symptoms, tell your doctor.
</BLOCK>


<BLOCK>
Headache, dizziness, high blood pressure, water retention may also occur.
</BLOCK>


<BLOCK>
The effectiveness of 
<EMPH weight="bold">
Syntopressin
</EMPH>
  may be reduced if you have nasal congestion, inflammation of the nostrils or a chest infection. Please tell your doctor.
</BLOCK>


</DIV>

</DIV>

</DIV>
<DIV type=1>

<HEAD weight="bold" >
Storing your medicine
</HEAD>


<BLOCK>
Keep you medicine in a safe place where children cannot reach it as your medicine may harm them.
</BLOCK>


<BLOCK>
You should keep unused sprays in the fridge. DO NOT allow to freeze. Allow the splay to reach room temperature before you use it for he first time.
</BLOCK>


<BLOCK>
Once the spray is in use you can store it at room temperature. Throw the spray away after one month of opening even if it is not finished.
</BLOCK>


<BLOCK>
The bottle contains a large volume of air for technical reasons.
</BLOCK>


<BLOCK>
If your doctor decides to stop your treatment, return any leftover medicine to your pharmacist. Only keep it if your doctor tells you to.
</BLOCK>


</DIV>
<DIV type=1>

<HEAD weight="bold" >
What's in your medicine?
</HEAD>


<BLOCK>

<EMPH weight="bold">
Syntopressin
</EMPH>

</BLOCK>


</DIV>
<DIV type=1>

<HEAD weight="bold" >
Further information
</HEAD>


<BLOCK>

<EMPH weight="bold">
REMEMBER
</EMPH>

</BLOCK>


<BLOCK>
This leaflet does not contain complete information about your medicine and the information given applies only to 
<EMPH weight="bold">
Syntopressin
</EMPH>
.
<EMPH weight="bold">
 
</EMPH>
If you have any questions or are unsure about anything ask your doctor or pharmacist.
</BLOCK>


<BLOCK>

<EMPH weight="bold">
Syntopressin
</EMPH>

<EMPH weight="bold">
 
</EMPH>
is a registered Trade Mark.
</BLOCK>

<PB n=7>
<CB n=2>

<BLOCK>
SANDOZ PHARMACEUTICALS <CB n=1> SANDOZ PRODUCTS (IRELAND) LIMITED <FIGURE></FIGURE>
</BLOCK>

</DIV>

</DIV>

</DOCUMENT>
