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'TEN O R ETI C'
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Please read this leaflet carefully before you take your medicine. This leaflet only gives a summary of the information available on your medicine.
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If you have any questions or are not sure about anything, ask your doctor or pharmacist.
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WHAT YOU SHOULD KNOW ABOUT YOUR MEDICINE
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The name of your medicine is 'Tenoretic'.
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The active ingredients are atenolol and chlorthalidone.
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'Tenoretic' is produced as tablets which contain 100 mg of atenolol and 25 mg of chlorthalidone.
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Your medicine also contains the following inactive ingredients:
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gelatin, iron oxide, macrogol, magnesium carbonate, magnesium stearate, methylhydroxypropylcellulose, sodium lauryl sulphate and maize starch.
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'Tenoretic' tablets are produced in packs of 28, 30, 500 and 504 tablets. Some of the pack sizes quoted are not available.
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Atenolol is one of a group of drugs called beta blockers. It has effects on the heart and circulation. Chlorthalidone is one of a group of drugs called diuretics. It increases the amount of urine produced by the kidneys.
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The product licence holder and manufacturer of 'Tenoretic' is:
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ZENECA Limited
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 Macclesfieid Cheshire United Kingdom 'Tenoretic' is used to treat hypertension (high blood pressure).
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Do not take Tenoretic' if you have previously had an allergic reaction to it or to atenolol or chlonhalidone.
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'Tenoretic' should not be taken by people with heart failure which is not under control or with cenain other conditions such as heart block, very slow or very Irregular heart beats, very low blood pressure or very poor circulation. h should also not be taken by people who have phaeochromocytoma which is not being treated or by people who have metabolic acidosis. Your doctor will know about these conditions.
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Do not take 'Tenoretic' if you are pregnant or if you are breast feeding a baby
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Do you have a particular type of chest pain called Prin2metal's angina7 If so, tell your doctor.
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Do you have asthma or do you get allergic reactions to such things as insect stings7 If so, tell your doctor Do you have diabetes7 'Tenoretic' may change your normal response to low blood sugar, which usually involves an increase in
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Do you have thyrotoxicosis7 Tenoretic' may hide the symptoms of thyrotoxicosis.
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Do you have kidney problems7 If so, talk to your doctor because you may need to have some check ups during your treatment.
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Are you taking any other medicines? If so, tell your doctor. Tenoretic' can intedere with the action of some other drugs and some drugs can have an effect on 'Tenoretic' The drugs which can cause some problems when taken together with 'Tenoretic' are verapamil, diltiazem, nifedipine (which are used to treat hypertension or angina), disopyramide (for irregular hean beats), digoxin if or heart failure), adrenaline (a heart stimulant). ibuprofen and indomethacin (for pain and inf)ammation) and lithiumZfor depression)
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Are you taking a drug called clonidine (for hypertension or migraine)7 If you are taking clonidine and Tenoretic' together. you must nor stop taking clonidine unless your doctor te))s you to do so If it becomes necessary for you to stop taking the c)onidine, your doctor will give you careful instructions on how to do it.
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If you go into hospital to have an operation, tell the anaesthetist or the medical staff that you are taking 'Tenoretic'
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Your medicine is unlikely to affect your ability to drive or to operate machinery, However, some people may occasionally feel diz2y or tired when taking 'Tenoretic' If this happens to you, ask your doctor for advice.
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TAKINGii YOUR MEDICINE
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 Tenoretic' tablets should be swallowed Follow your doctor s instructions about when and how to take your medicine Also read the label Your pharmacist can also help if you are not sure,
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Your doctor will have decided what dose you should take each day depending on your condition The usual daily dose for an adult is one tablet.
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If you forget to take your medicine, take your dose when you remember and then take your next dose at the usual time. Don't take two doses at the same time. If you are worried, ask your doctor or pharmacist for advice.
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If you accidentally take an overdose of your medicine, either call your doctor straight away, or go to your nearest hospital casualty department, Always take any remaining tab)ets, the container and the label with you, so that the medicine can be identified.
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Do not stop taking your medicine without talking to your doctor first. In some cases, it may be necessary to stop taking the medicine gradual)v
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AFTER TAKINGi YOUR MED CLNE
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 As with all medicines, undesirable events can sometimes be experienced with Tenoretic', Occasiona)ly, a few people can suffer from cold hands and feet. tiredness, s)ow hean beat, headache, dry mouth, nausea, diarrhoea, disturbed s)eep, thinning of the hair, mood changes, confusion. psychoses or hal)ucinations, bruising more eas)ly or purplish marks on the skin, tingling of the hands, dry eyes, distilrbances of vision, skin rashes, worsening of psoriasis or dizziness particularly when standing up Other possible events which may occur irl susceptible people are numbness and spasm in the fingers IRaynaud's phenomenon), heart block (which can cause ditziness or fainting), worsening of heart fa)lure in people with heart fai)ure, worsening of breathing difficu)ties in peop)e with asthma or breathing problems or worsening of the circulation in people with poor circulation, Other possible events are a reduction In the amount of potassium in the blood, an increase in the amount of uric acid in the biood or a reduction In the number of white blood cells Your doctor may take blood samples every so ohen to check on these levels
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Do not be elarmed by this list of possible events You may not have any of them.
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If you get any other undesirable events or if you think your medicine is causing any problems, tell your doctor or pharmacist SiTORINtti YOUR MEDICINE Check the expiry date on the carton and don't use the medicine afler that date, Keep your medicine in a safe plece where children cannot see it or reach it. Your medicine could harm them
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Keep your medicine below 25°C and away from strong light and dampness.
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If your doctor decides to stop treatment, return any leh-over tablets to your pharmacist. Only keep them if the doctor tells you to Date of preparation of leaflet: June '995
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FURtflER INiORII:(^;llON This leaflet does not contain the complete information on Telloretic'. If you have any questions, or are not stire about anything, ask your doctor or pharmacist
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Remember: This medicine is for you Only a doctor can prescribe it for you. Never give it to someone else. It may harm fflem even if their symptoms are the seme as yours.
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The information applies only to Tenoretic'.
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Tenoletic' is a trademark 6/lE/UK 1014711
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