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Immukin Interferon gamma–1b
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What you should know about IMMUKIN Vials for Injection   
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Please read this leaflet carefully before you start to take your medicine.  It contains a summary of the information available on your medicine.  The information in this leaflet applies to IMMUKIN only.  If after reading this you have any questions ask your doctor or pharmacist.
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The name of your medicine is IMMUKIN Injection.  Each vial is for single use only and contains 100 micrograms of an active ingredient named recombinant human interferon-gamma-1b.  It also contains the following inactive ingredients:
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mannitol, disodium succinate hexahydrate, polysorbate 20 and succinic acid.
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IMMUKIN is available in packs of 6 vials
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IMMUKIN is a medicine which works with your immune system to help your body fight infection.
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The Product Licence / Authorisation for IMMUKIN is held by:
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Boehringer Ingelheim Limited, Ellesfield Avenue, Bracknell, Berkshire RG12 8YS and IMMUKlN is manufactured by
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Genetech Inc.,
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460 Point San Bruno Boulevard, South San Francisco, CA 94080, USA
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How IMMUKIN helps you
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IMMUKIN is used to help reduce infections in patients with diseases which affect the white blood cells.  Consult your doctor for further information.
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Before you use your medicine:
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Remember to tell your doctor or pharmacist if:
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You are pregnant or likely to become pregnant.
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You intend breast feeding.
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You are taking any additional medicines (prescribed or bought) and particularly if you are considering vaccination.
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You have had kidney or liver disease.
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You have had fits or heart disease.
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Do not use IMMUKIN if you have experienced an allergic reaction to it or a similar medicine.  Tell your doctor if you develop a rash
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Do not give IMMUKIN to children who are less than 6 months old.
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Do not use your IMMUKIN vial if you can see any particles in the liquid.
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Do not mix IMMUKIN with other drugs in the same syringe.
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Your doctor may want to perform regular blood tests to monitor your medical condition.
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IMMUKIN may alter your ability to drive or operate machinery and this may be made worse by alcohol.
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How to use your medicine
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 <PB n=3> <CB n=1> Follow your doctor’s instructions about when and how to use your medicine. More detailed information is available in a booklet ‘Taking Care’, a guide for patients and carers who regularly administer IMMUKIN, which is available from your doctor
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IMMUKIN is normally given three times a week on alternate days.  It is injected under the skin.  The dose is calculated according to body surface area as follows:
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The usual recommended dose for patients with body surface areas greater than 0.5m2 is 50 mcg/m2.  A dose of 1 5 mcg/kg is recommended for patients whose body surface area is less than 0.5m2 <CB n=2>
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Do not take more than the dose your doctor has prescribed.  If you think you have taken an overdose of IMMUKIN, tell your doctor
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Throw away any unused medicine remaining in the vial.  It is important to use the injection immediately after the vial is opened.
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Keep using your medicine until your doctor tells you to stop.
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What to do if you forget to use your medicineHow to store your medicine
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If you remember 
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more
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 than 12 hours before the next dose is due: inject the missed dose when you remember and the next dose at the usual time.
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It you remember 
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less
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 than 12 hours before the next dose is due: do not inject the missed dose.  Simply inject the next dose at the normal time
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After injecting your medicine:
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All medicines sometimes cause side effects
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You may feel hot or cold and suffer headache, feelings of weakness, tiredness and nausea. These effects will decrease as your treatment continues.
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IMMUKIN can cause vomiting, joint pain and tenderness at the site of injection, but these side effects only occur in very few patients
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IMMUKIN can cause a rash, which will usually disappear without having to interrupt your treatment.
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If you experience any other unusual or unexpected symptoms consult your doctor or pharmacist.
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Do not use this medicine after the expiry date which you will find printed on the packaging.  Keep vials in a refrigerator (2-8ºC) and do not freeze.  Do not shake the vials vigorously.
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Keep this medicine in a safe place where children cannot reach it.
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REMEMBER this medicine is for you.  Only a doctor can prescribe it for you.  Never give it to others. It may harm them even if their symptoms are the same as yours.
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This leaflet was issued in September 1994.
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